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The recommended daily dose is 1mg of folic acid, and anything above that amount might lead to negative effects like diarrhea, nausea, skin reactions, bloating, or stomach pain

50 , 637718 (1970) Sies, H., Gerstenecker, C., Summer, K.H., Menzel, H., Floh, L.: Glutathione-dependent hydroperoxide metabolism and associated metabolic transitions in hemoglobin-free perfused rat liver

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doi: 10.1515/cclm.2003.195 27 Le BrasMClmentMVPervaizSBrennerC

Guder WG, Ross BD (1984) Enzyme distribution along the nephron