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doi: 10.1016/j.pain.2010.11.005

They can be easily synthesized in various cells, coupled to different substances, and modified in different manners

As an agonist of the growth hormone secretagogue receptor (GHS-R)the same receptor targeted by ghrelin, often referred to as the ghrelin receptorit stimulates the release of GH from the anterior pituitary gland

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Echoing the scientific literature, they write of ipamorelin that we lack sufficient information to know whether the drug would cause harm if administered to humans via [injection]. The peptide pralmorelin (or GHRP-2) is clinically approved in Japan, but only as a way to diagnose adults who are deficient in growth hormone

Given their more sophisticated behavioral variety and brain similarity with humans, non-human primates (rather than rodents) should receive more attention in the later stages of preclinical drug research