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A summary of the main factors influencing GLP-1 secretion is shown in the image below (Huber et al, 2024)

In contrast, the Cagri-AMY 2 R-Gs complex was stable in the consensus AMYR conformation with stable TM interaction between RAMP2 and CTR, and the peptide maintained a bypass motif

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Punicalagin (CAS 65995-63-3) and punicalin (CAS 65995-64-4) were obtained from BOC Science (Shirley, NY, USA) and Apollo Scientific (Stockport, UK), respectively