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Semaglutide-induced nausea, which affects up to 44% of people taking the higher doses , can trigger retching and vomiting

Prominent in neurons, but not glial cells, GIP synthesis is more distributed in the CNS compared to GLP-1 and was identified in the hippocampal CA1-3, granule cell layer and neurogenic niche of the dentate gyrus, thalamus, cerebral cortex, cerebellum (Purkinje cells) and brainstem

At MetFit-Rx, this doesn't mean casually taking less medication

Multiple publications from Zagreb group, 2009 to 2020 range

However, compounded GLP-1 is not appropriate for patients with personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia type 2, severe renal disease, or active gastrointestinal disorders requiring specialist supervision

NCBI Bookshelf NBK5274