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Pellets were resuspended in 20 ml cold 0.2% NaCl for 30 s, followed by addition of 20 ml cold 1.6% NaCl to lyse remaining erythrocytes

Liposomal curcumin has reached phase I evaluation in patients with locally advanced or metastatic cancer (ClinicalTrials.gov lists a study of liposomal curcumin combined with radiotherapy and temozolomide in newly diagnosed high-grade gliomas ( The translational message is therefore sobering but useful

The free B12 binds to a protein called R-binder (haptocorrin) in the stomach

In the SURMOUNT-1 obesity trial, tirzepatide produced mean weight reductions of roughly 1521% depending on dose over 72 weeks ( Jastreboff et al., NEJM 2022