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Hansen, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Clinical advantages: Decreased pain and inflammation Augmented cellular-level healing Fully autologous, minimizing risk of adverse reactions Safe with minimal risk of rejection or infection Autologous Conditioned Serum (ACS) Also referred to as Regenokine or Orthokine, ACS is derived from the patients blood, incubated to elevate anti-inflammatory cytokines, notably Interleukin-1 Receptor Antagonist (IL-1Ra), which counteracts destructive inflammatory processes in joint pathology

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