Researchers observed that weight loss with semaglutide ranged from 9.6 to 17.1% in participants without gastrointestinal AEs and from 11.4 to 17.7% in those with gastrointestinal AEs, suggesting gastrointestinal AEs appeared to contribute little to the weight-loss benefit of semaglutide, which were consistent with previous studies that the weight-loss effects of semaglutide in patients with obesity and/or T2DM indicated little contribution of gastrointestinal AEs (26, 36, 37)
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At two or more years after starting treatment, the odds of a new diagnosis of alopecia in GLP-1 users were 37% higher than in users of so-called SGLT-2 drugs and 68% higher versus DPP-4 drugs, researchers at the University of Pennsylvania reported on Wednesday in The BMJ
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Dehydration, in turn, is a well-recognised risk factor for kidney stone development and may also lead to acute kidney injury
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