Volpe S, Lisco G, Fanelli M, Racaniello D, Colaianni V, Triggiani D, Donghia R, Crudele L, Rinaldi R, Sabb C, Triggiani V, De Pergola G, Piazzolla G
If nausea limits your exercise tolerance, particularly in the first hours after injection, schedule workouts for non-injection days or later in the day when nausea has subsided
Those who received Wegovy lost roughly 35 lbs (15.9 kg) compared to the 6 lbs (2.7 kg) weight loss in the placebo group
A conservative approach might start at 2.5mg twice weekly for the first week, then 5mg once weekly the second week, before moving to 5mg twice weekly if tolerated
Tirzepatide (Mounjaro, Zepbound) is a dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor agonist, though these medications are often collectively referred to as incretin-based therapies
The STEP 1 trial extension showed that participants regained two-thirds of their prior weight loss within one year of stopping