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Despite the differences between compounded and FDA-approved GLP-1s, compounders continue to eat into the profits of large drugmakers

The short answer is yes, but the reasons why (and how long it lasts) arent always straightforward

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There is no significant interaction with renal function, and the benefits of GLP-1 RAs remain consistent irrespective of the timing of patient inclusion in the trials

Slower titrationstaying at a lower dose for longercan sometimes improve tolerability whilst still providing therapeutic benefit