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Semaglutide GLP-1 mimics a naturally produced hormone that promotes feelings of fullness for longer periods and reduces harmful habits such as overeating and snacking

Patients achieving a 5% reduction from baseline in body weight was a co-primary outcome in the STEP 1 to STEP 3 studies, and there were greater percentages of patients in the semaglutide group than in the placebo group who achieved a 5% weight loss by week 68 in each of STEP 1 (odds ratio [OR] = 11.22 [95% CI, 8.88 to 14.19

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10.1016/j.eclinm.2024.102782 [DOI] [PMC free article] [PubMed] [Google Scholar] Alsugair H