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Using a modified Delphi process and a structured evidence-grading framework, experts reviewed data on: - COVID-19 and influenza vaccine efficacy - Adverse events related to CSIs - Effects of CSIs on the hypothalamicpituitary axis - Incidence of COVID-19 and influenza in patients receiving CSIs - Appropriate intervals between CSIs and vaccination Key Recommendations: For non-urgent indications, offer CSIs at least 1 week before or after COVID-19 or influenza vaccination

Guilherme A et al

Biomaterials 51 , 238249 (2015)

Common side effects are minimal and localizedmild soreness, redness, or bruising at the injection site typically resolve within hours to days

A patient with insufficiency needs a maintenance dose

When to choose GHK-Cu GHK-Cu is the better choice for broader regenerative goals