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If the question is about repeated signaling, split administration may make more sense than a one-time daily exposure

Accordingly, production of the endogenous antioxidant glutathione (GSH) by glial cells within the brain [8], particularly astrocytes [8,9,10], is a critical function, as most antioxidants are unable to cross the blood brain barrier

Recycling of oxidized GSH (GSSG) back to its reduced form is facilitated by glutathione reductase (GSR) using NADPH from the pentose phosphate pathway

So, we put energy/frequencies into pills, and those energies/frequencies directly enhance cell functioning

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