Weight reduction is dose-dependent, reaching 15.4% at 36 weeks (Table 1), without evidence of a plateau, and is accompanied by a reduction in CVRFs38 (Fig
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The incretin hormones GIP and GLP-1 are important substrates for DPP-4 action, while increased DPP-4 activity is associated with lower levels of GIP and GLP-1 [3]
If you are taking any GLP-1 medication and plan to switch to another one, always start the new medication at the lowest dose and titrate it gradually to minimize the risk of side effects
Its best for people who want GLP-1 benefits without major weight loss or who are sensitive to side effects
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