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Microbiota alteration is associated with the development of stress-induced despair behavior

Astroglial pathophysiology is complex, with different pathophysiological cell states and cell phenotypes that are context-specific and vary with disorder, disorder-stage, comorbidities, age, and sex

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The OD value at 490 nm was detected by an enzyme marker

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This dual nature of HS is largely attributed to imbalances in its concentration, which are thought to be influenced by three key factors: (1) the limited capacity of intracellular HS detoxification and diffusion mechanisms, (2) alterations in the gut microbiota, and (3) dysregulation of endogenous HS metabolism [87]