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This work is supported by Young Scientist grant by Indian National Science Academy (INSA/SP/YSP/152/2018/232), DST-FIST Program (No

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This magnitude of weight loss narrows the gap with bariatric procedures, although it remains below the average 25%-35% weight loss typically reported after sleeve gastrectomy or Roux-en-Y gastric bypass [6] , reinforcing the therapeutic potential of dual-pathway targeting