B Vitamins Riboflavin is a necessary coenzyme for the activity of glutathione reductase, which converts the oxidized glutathione into its reduced form, the compound required for antioxidant function [82]
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Consequently, FIN56 inhibits Sec integration into the catalytic subunit of GPX4, reducing its antioxidant capacity ( 4.2 Non-enzymatic pathway of ferroptosis 4.2.1 Iron homeostasis Iron is crucial for living organisms, and its deficiency can cause health issues
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[DOI] [PMC free article] [PubMed] [Google Scholar] 188.Vayalil P.K., Landar A