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However, the question remained on whether the possible beneficial therapeutic actions of GLP-1 RA in PCOS might depend exclusively on the improvement in body weight and metabolic profile or on direct effects on HPG axis in PCOS

In skeletal muscle, AKT phosphorylation activates mTORC1, increasing ribosomal protein S6 kinase activity and protein translational efficiency the primary molecular mechanism underlying the hypertrophic stimulus

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It is worth noting that GLP-1 receptor agonist treatment in obese PCOS patients can be a new therapeutic option beyond the goal of weight loss, the researchers wrote

An emerging area of AD research highlights the contribution of chronic viral infections, particularly members of the Herpesviridae family, to neurodegeneration and disease progression 45,46,47,48,76,77

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