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The accelerated approval was granted based on initial overall response rate (ORR) of 57% in 164 treatment-nave patients and duration of response (DOR)40% of responders had a duration of response greater than 12 months, according to the FDAs full approval announcement

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Identification of oxadiazoles as new drug leads for the control of schistosomiasis

PGN modification, charge and integrity alterations of the cell wall, and the synthesis of muramidase inhibitors [9]

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