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GLP-1 Effects May Promote a Fasting-Like State Because GLP-1 agonists: Reduce appetite Delay gastric emptying Sometimes cause nausea or vomiting The body may enter a relative fasting state

Studies showed that retained gastric fooda common symptomhas only 32-67% positive predictive value depending on the patient population

7.4, p = 0.015)

In addition, the autonomic nervous system is actively involved in the process

Simultaneously, the state of calorie deficit itself creates a catabolic environment, where the body breaks down tissue to meet energy demands