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Notable findings from these studies include the qualitative differences in immune response induced by different platforms (e.g., Ad vs

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Groups 2 and 3 (MC1&MC2) were given MC at doses that corresponded to 1/40 and 1/20 of the LD 50 , respectively (125 and 250 mg active ingredient/kg bwt that equivalent to a human dose of 20- and 40 mg/kg bwt)

The steady state exposure of WEGOVY increased proportionally with doses up to 2.4 mg once weekly