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The most common side effect patients experience is nausea, but just like all the other effects you may experience, it is completely temporary

But people who have long COVID usually have some component of orthostatic intolerance, whether it be ME/CFS or POTS it's going to be there

People who are pregnant may want to check with a healthcare provider before drinking yerba mate.[2] What Are Potential Side Effects of Yerba Mate

The breadth of documented effects comes from the peptides role as a gene expression regulator

It's quite popular in foundations

The Cys is essential for taurine and glutathione (GSH) synthesis, both of which possess antioxidant properties (Mtayer et al., 2008) ( Figure 1 )