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Campylobacter jejuni and Campylobacter coli are the major causes of bacterial gastroenteritis, while Arcobacter species are also known to be human and animal pathogens

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doi: 10.1016/j.main.2014.07.001

High-throughput deep mutational scanning, informed by AlphaFold, further pinpointed residues in CaErg11 that alter azole binding and resistance (Desprs et al., 2022)

Corroborating this pathogenic axis, recent studies using cortical neurons derived from patient induced pluripotent stem cells (iPSCs) have demonstrated that presenilin-1 mutations (F105C and A246E) induce pronounced mitochondrial defects, which are remarkably rescued by amyloid precursor protein (APP) knockout, identifying APP as a critical bridging mediator of familial AD-associated mitochondrial dysfunction [45]