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Side effects and safety profiles compared This is where the conversation gets complicated

Non-oral contraceptives, such as intrauterine devices (IUDs), transdermal patches and implants, are unlikely to be affected as their active ingredients are absorbed into the blood stream independently of the gastrointestinal tract

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But as the medications reach a larger market, more side effects, some potentially good and others decidedly not, have cropped up

Insulin therapy, especially if not well managed, can lead to hypoglycemia (low blood sugar levels), which can disrupt sleep

Beutler E, Moroose R, Kramer L, Gelbart T, Forman L: Gamma-glutamylcysteine synthetase deficiency and hemolytic anemia