Its known that 22 splice variants of hTERT exist (Plyasova and Zhdanov 2021) however, only the full-length variant codes for the fully active telomerase enzyme and some variants can act in a dominant negative way to inhibit telomerase activity
We therefore extended these studies by testing whether hypophagia induced by chemogenetic activation of PPG NTS neurons was followed by compensatory rebound hyperphagia, or elicited significant disruption to the behavioural satiety sequence, using the excitatory hM3Dq DREADD (Fig
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