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Within the Wnt/-cateninVEGF axis, oridonin (ORI), an ent-kaurane-type diterpenoid isolated from the aerial parts of Rabdosia rubescens (Thunb.) Hara (Lamiaceae), has been shown to activate Wnt3a/-catenin signaling and upregulate VEGF expression, thereby promoting Type H vessel formation and enhancing bone density and structural regeneration (Yu et al., 2023, PMID: 36924567)
Parallel reporter assays identify altered regulatory role of rs684232 in leading to prostate cancer predisposition
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So does eating enough protein and nutrients that help your body form collagen in the first place
Am J Med Genet Part C Semin Med Genet