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Herpes simplex viruses (HSVs) are one of the most prevalent neurotropic viruses, including HSV type 1 and type 2 (HSV-1 and HSV-2) (James et al., 2020), which establish lifelong latent infection in keratinized epithelial surface, and sensory neurons and dorsal root ganglia of the peripheral nervous system (He and Han, 2023

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There was no role of the funding body in the design of the study and collection, analysis, and interpretation of data and in writing the manuscript should be declared

These biomarkers can be categorized into traditional biochemical markers and emerging molecular biomarkers