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However, these studies only utilized the activation of ATF4 and its downstream target genes as markers of UPR activation

Hayashida K, Sano M, Ohsawa I, Shinmura K, Tamaki K, Kimura K, Endo J, Katayama T, Kawamura A, Kohsaka S, Makino S, Ohta S, Ogawa S, Fukuda K

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However, since the primary role of NAC as an antioxidant stems from its ability to increase the intracellular concentration of glutathione, it can help provide your body with a more consistent supply

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