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A slight modification of the eCATH-3 peptide (LLK-eCATH-3) realized by the substitution of only three amino acids caused a higher hydrophobicity and helical content resulting in a dramatic change of the antimicrobial activity

Even though most people experience occasional constipation, this condition is sometimes serious and may require medical attention

In addition to the disruption in iron homeostasis, nuclear receptor coactivator 4-mediated ferritinophagy can lead to iron accumulation and ferroptosis [24]

Data availability Source data underlying graphs presented in the main figures can be found in Supplementary Data 1 and are available from the corresponding author on reasonable request

Commonly reported side effects can include: Site Injection Pain/Irritation: This is common with many peptides, especially if the solution is not at the correct pH

How is Tirzepatide administered