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No other significant differences were shown at subsequent follow-up times (Figure 5)

This model supports comprehensive analyses of treatment-induced changes in liver histopathology (pre-to-post histopathological scores and terminal quantitative histology), plasma/liver biochemistry, metabolic markers, and global hepatic transcriptional profiles, thereby facilitating both efficacy readouts and mechanistic characterization

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A and B: Before/after pictures: A: Taken at the beginning of the study

Retrieved February 22, 2016, from 2 Geppetti P, et al

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