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Further studies have shown that PKC directly phosphorylates Ser 40 within the Neh2 domain of NRF2, which is necessary for the dissociation of NRF2 from Keap1 [41]

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( b ) Representative dose-response curves of cAMP assays with GLP-1, AMG 133 or hGIPR-Ab/P1 in cells expressing human GLP-1R