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doi:10.1007/s12031-023-02164-5 Sun-Edelstein C, Mauskop A

BPC-157 may not be appropriate when: Imaging or specialist review has not yet been completed for a suspected structural injury There are acute red flag features (severe weakness, fever, rapid unexplained swelling, neurological changes, unexplained weight loss) The patient has active cancer or a history of certain cancers where angiogenic peptides require careful risk assessment The goal is rapid results without addressing underlying load, rehabilitation, or lifestyle drivers A peptide should not be used to delay evaluation that is clearly warranted

Expected timeline: Week 1-4: Multiple peptides beginning effects across different symptom domains

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Administer 5-Amino-1MQ concurrently or add NAD+ precursors like NMN (nicotinamide mononucleotide) at 250500 mg/kg daily

This may potentially allow for lower thrombolytic drug exposure and reduced risk of hemorrhage