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Research published in the Journal of Gerontology by Grove and Kligman found that stratum corneum transit time was approximately 20 days in young adults but lengthened by more than 10 days in older adults (PMID: 6827031)

The reaction progress was tracked by coupling formate release to NADH oxidation by formate dehydrogenase

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For example, Bifidobacteria metabolize and produce antioxidant substances such as vitamin K and GSH precursors, which can reduce cellular sensitivity to ferroptosis by regulating lipid metabolism (124)

doi: 10.3389/fonc.2022.997919 Received 19 July 2022 Accepted 28 November 2022 Published 19 January 2023 Volume 12 - 2022 Edited by Cinzia Domenicotti, Universit di Genova, Italy Reviewed by Barbara Marengo, University of Genoa, Italy