Our focus is understanding the interactions between bile acids (Bas) and the gut microbiota, abnormal lipid metabolism, and the suppression of plasma glucagon-like peptide-1 (GLP-1) levels in HTH conditions
Semaglutide, a GLP-1 receptor agonist originally developed for type 2 diabetes, has demonstrated significant weight loss benefits in clinical trials, with participants losing up to 15% of body weight over 68 weeks
Factors that limit results include inadequate protein intake, metabolic adaptation, medication non-compliance, and unrealistic timelines
Other factors, like stress, existing medical conditions, or interactions with other medications, might play a role
Some dont feel any effect, whereas others get headaches
is supported by the Portuguese Fundao para a Cincia e Tecnologia (FCT) (grant number SFRH/BPD/77448/2011, part of the EDCTP2 program supported by the European Union)