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Injection-Related Challenges Since Semaglutide is administered via injection, some people may feel uncomfortable with self-injections or experience mild bruising or irritation at the injection site

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From a mean baseline body weight of 96 kg after randomization, there was a mean reduction of 0.3 kg in the patients who received insulin detemir add-on therapy compared to a mean reduction of 1.1 kg in the patients who continued on unchanged treatment with liraglutide injection 1.8 mg + metformin alone

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