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UA is a highly efficient scavenger of ONOO and inhibits ONOO -mediated tyrosine nitration

This can lead to respiratory arrest, brain damage, or death if not promptly treated

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While this concept is undoubtedly real, what influence it actually exerts on disease is unclear

"High frequency of vitamin B12 deficiency in asymptomatic individuals homozygous to MTHFR C677T mutation is associated with endothelial dysfunction and homocysteinemia"

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