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These substrates are coupled by transfer enzymes to endogenous metabolites (e.g., glucuronic acid and its derivatives, sulfuric acid, acetic acid, amino acids, and the tripeptide glutathione) in reactions that often involve high-energy intermediates (Table 4-2)

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Pharmacologic Overview of GLP-1 Receptor Agonists Mechanism of Action Endogenous GLP-1 is an incretin hormone secreted by intestinal L-cells postprandially

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