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Scholar Ogiwara H, Takahashi K, Sasaki M

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These preclinical models allow scientists to investigate key GLP-1 therapeutic pathways, including insulin secretion, glucagon production, gastric emptying, and satiety

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Research in cell and animal models demonstrates its capacity to suppress NF-kB activation, reduce pro-inflammatory cytokine release including IL-1b, TNF-alpha, and IL-6, and interact with melanocortin receptors on immune and intestinal epithelial cells