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Prior to formulating incretin mimetics, two administration issues had to be resolved - their lack of oral bioavailability and their short half-lives [23]

Rather than directly impairing osteoclasts, it targets the signaling protein RANK ligand, which is required for osteoclast generation, thereby reducing osteoclast formation and activity through an immune-mediated mechanism

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Pepto-Bismol should be stored at room temperature (20-25 degrees Celsius/68-77 degrees Fahrenheit), preferably in the kitchen cabinet rather than the bathroom cabinet, as light and humidity can interfere with the efficacy