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13a, Supplementary Table 9), suggesting that the distinct rotamer orientation of H296 ECL2 in Cagri-bound CTR (to accommodate the Glu linker) and/or the observed more open ECL3 conformation induced by the lipidated peptide may facilitate or stabilize an active CTR conformation (Supplementary Fig

This was taken as an effective upgrade of the cytoprotection principle of endothelium maintenance epithelium maintenance [5,6,66,71,72,73,74,75,76,77,78,79,80,81,82] (note, long ago, the principle of cytoprotective agents pleiotropic beneficial activities postulated the founding of two major groups of (stomach) studies: Robert (epithelium maintenance) and Szabo (endothelium maintenance) [35,36,37,38,39,40,41,42] (for review, see [32,33,34])

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