Compared with other antidiabetic medications, including SGLT2 inhibitors, DPP-4 inhibitors, and thiazolidinediones, semaglutide was associated with a lower risk of major adverse liver outcomes (MALO), such as decompensated cirrhosis, liver cancer, and liver transplantation
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Hydration Management: Adequate hydration remains essential, particularly given semaglutide's gastrointestinal effects