glp 1 nejm 𝗧𝗵𝗲 𝗘𝗳𝗳𝗲𝗰𝘁 𝗼𝗳 𝗚𝗟𝗣-𝟭 𝗥𝗲𝗰𝗲𝗽𝘁𝗼𝗿 𝗔𝗴𝗼𝗻𝗶𝘀𝘁𝘀 𝗼𝗻 𝗚𝗹𝘆𝗰𝗮𝘁𝗲𝗱 𝗛𝗲𝗺𝗼𝗴𝗹𝗼𝗯𝗶𝗻 𝗟𝗲𝘃𝗲𝗹𝘀 ⁣ ⁣ Randomized, placebo-controlled trials of the glucagon-like peptide-1 (GLP-1) receptor agonists have provided strong GLP1 receptor agonist @nejm revisión

Liraglutide in Obese or Overweight Individuals With Stable Bipolar Disorder

Immunity 48 , 11441159.e5 (2018)

Common gastrointestinal side effects are the most frequently reported issues with GLP-1 therapy: Nausea and vomiting : Typically most pronounced during treatment initiation or dose escalation

In a study employing OGD/R models of BV2 cells, the intervention of vitamin K1 attenuated retinal inflammatory responses by moderating microglial ferroptosis, which was characterized by increased level of GPX4 and SLC7A11 (45)

Notably, the availability of GSH negatively modulates SLC25A39 protein levels, thereby linking redox homeostasis to mitochondrial GSH import in mammalian cells

As a highly expressed gene in resistant cells, PRKA kinase anchor protein 8L (AKAP-L8) can promote GC cells to acquire stem cell-like features by maintaining the stability of Stearoyl-CoA desaturase 1 (SCD1) via an IGF2 mRNA binding protein 1 (IGF2BP1)-dependent manner, resulting in resistance to oxaliplatin (63)