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In preliminary results of OASIS 1, a recent 68-week, phase 3a clinical trial that compared once-daily oral semaglutide with placebo in adults with obesity or overweight with one or more underlying comorbidities, the average weight loss from baseline was 15.1% in the semaglutide group and 2.4% in the placebo group

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The MHRA warning calls out Mounjaro, specifically, regarding the possible disruption of birth control, but then goes on to remind women that none of the drugs should be taken during pregnancy, as the effects on a fetus are unknown