Prescribers and patients approach treatment with weight reduction as the primary goal while cardiovascular benefits are viewed as additional advantages rather than primary treatment rationales
Luo Y, Yang S, Zeng H, Liu S, Zhang Y, Li JE, Liu J (2025) Both subcutaneous semaglutide and calorie restriction improves pancreatic cell hyperplasia and gut microbiota in high-fat diet-induced obese mice
However, these observations need to be confirmed by future trials [138]
To ensure consistency, the same analyses were also carried out in R software version 3.4.4 (R Project for Statistical Computing)
Retatrutide itself is still being studied, but approved incretin therapies can require careful glucose monitoring when used with diabetes medications that lower blood sugar
Clin Proc