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Acne scar treatment follows similar principles

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doi: 10.1007/s00003-021-01324-2 116

Compounds such as grape seed proanthocyanidins (GSPs) have demonstrated protective effects against DPN by alleviating endoplasmic reticulum stress and enhancing antioxidant defenses

For significant pigmentation reduction or de-tanning, a full protocol of 815 sessions is typically recommended, followed by monthly maintenance