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DET1 exhibited highly flexibility, with several regions missing in the reconstruction, including 5 (residues 162-186), 7-11 (residues 257-328) and 12 (residues 349-361)

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doi:10.3390/ijms18010200 Hell R, Bergmann L (1990) -glutamylcysteine synthetase in higher plants: catalytic properties and subcellular localization

B., Goldstein, H

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Regarding mental health, clinical trial data for tirzepatide have not identified significant concerns related to depression or anxiety as direct adverse effects