Nitroglycerin can exert vasodilation in the arteries at higher doses which results in a decrease in the pressure the heart must exert (termed afterload) to expel blood from the left ventricle, thereby, adding to reduced cardiac oxygen demand
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Topol is no fan of supplements, avoids ultra-processed foods, follows a Mediterranean diet with no red meat at all, has non-fat Greek yogurt with berries and granola for breakfast, eats mostly nuts for lunch and has a large salad sometimes topped with salmon for dinner after which he doesnt eat anything
Miller R, Buehner G, Chang Y, Harper JM, Sigler R, Smith-Wheelock : Methionine deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF-1 and insulin levels and increases hepatocyte MIF levels and stress resistence