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The Sphincter of Oddi regulates bile release from the gallbladder into the small intestine.18 If thyroxine is deficient, less bile may be released into the small intestine, contributing to SIBO and/or constipation

10.1007/s11033-020-05302-z 11 ChangA.ChangY.WangS

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It is produced naturally in the liver and is found in nearly every cell in the human body

Treatment with low-dose dexamethasone (10 mg/day) for 6 months allows most patients to stop taking corticosteroids and reverses drug-related adverse effects while maintaining clinical remission

I am not certain why this happens, and it doesn't appear to have a lasting effect