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PBMCs from healthy donors were differentiated with GM-CSF (2050 ng/mL) for 6 days, followed by polarization with LPS (100 ng/mL) and IFN- (2050 ng/mL) for 12 days

certain mechanisms are more prevalent in specific tissues

Experiments revealed that negatively charged MSNs could function as nanocarriers capable of crossing the BBB and delivering drugs without relying on external stimuli or ligand/receptor protein interactions[80]

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