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Exendin-4 bound to same receptors as GLP-1, stimulated insulin secretion in rodents, and lasted longer in the body thanks to a mutation that protects it from being cut up by enzymes

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Study outcomes included the number needed to treat (NNT) to prevent one case of clinical events, healthcare costs, and cost per case of event prevented

Some 70% of all GLP-1 users actively conduct product or health research to support their weight-loss journeys

Ruhl, C

Updated guidance for trusted systematic reviews: A new edition of the Cochrane Handbook for Systematic Reviews of Interventions