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Therefore, to explore whether there is an association between neutrophils and ferroptosis, another study explored the role of GPX4 in neutrophil ferroptosis and identified two key factors, namely serum autoantibodies and IFN- (170), both of which induce iron apoptosis in neutrophils by activating the CaMKIV/CREM axis, leading to SLE neutropenia

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Ma X, Liang X, Li Y, Feng Q, Cheng K, Ma N, Zhu F, Guo X, Yue Y, Liu G, et al